IV Fluid Therapies for Fluid and Electrolyte Imbalance

Posted on: 10th May 2023

Question

Describe the process by which fluid and electrolytes maintain homeostasis at the cellular level.

Identify tonicity of common IV fluids and their uses. Include how the tonicity affects fluid shifts at a cellular level.

Identify nursing assessment and care of the patient with fluid and electrolyte disturbances who require I.V. therapy.

Describe the process by which fluid and electrolytes maintain homeostasis at the cellular level. Consider osmosis, diffusion, intra and extra cellular pathophysiology.

Identify tonicity of common IV fluids and their uses. Include how the tonicity affects fluid shifts at a cellular level. Consider hypertonic, isotonic, hypotonic and colloid solutions.

Identify nursing assessment and care of the patient with fluid and electrolyte disturbances who require I.V. therapy. What will you monitor? What are priorities?

Students will write an APA paper using 7th ed. APA student formatting describing, in the students own words, the relationship between fluids and electrolytes in maintaining homeostasis, the purpose of intravenous therapy and nursing considerations. The paper will be a minimum of three (3) pages (excluding title and reference page) with at least 2 references, one of which must be the article titled Fluid and Electrolyte Imbalances by Molly McClelland,

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Solution

IV Fluid Therapies for Fluid and Electrolyte Imbalance

Biological systems maintain homeostasis, which is defined as a process of continuous physiological, mechanical, and metabolic circumstances. This is a state of optimal health for an animal in which several parameters, like average temperature and adequate fluid, are maintained within pre-determined boundaries. Since the quantity of fluid, a region holds is directly proportional to the number of ions in it, ions, especially sodium, assist the body in maintaining a stable hydration equilibrium in the interstitial fluid. Fluid will flow into such partitions if the ions' content is increased. Fluid will flow out of the chamber if the ionic content is low. The body can actively transfer ions into or out of cells to support water balance. Maintaining water levels between partitions necessitates ions in the proper quantities.

Osmosis, a mechanism that governs the concentration and structure of water and electrolytes in the compartments, transports fluid across them. The osmotic pressure inside the participant's organs controls the degree of osmosis. Water is drawn across semipermeable cells like cell membranes under this tension. Osmotic pressure can cause fluid to flow into or out of the cellular response. The degree of osmolality is determined by the ratio of electrons in injected solutions to ions in cell fluid. Fluid moves from zones of less ionic concentration to a greater concentration of ion zone (McClelland, 2014). Fluid travels into and remains in the interstitial fluid when the amount of protein particles in serum is insufficient, as in diabetic ketoacidosis or the protein-calorie deficiency known as "kwashiorkor." The flow rate in the third space, also known as third-spacing, is a sort of hydraulic shifting in the third space. Fluids get stuck in the intermediate and intracellular compartments, as well as in a third-body region, where they are unable to circulate.

The tonicity of I.V. solutions, or the fraction of solute molecules in solution, affects physiologic flowing fluid. Contrary to normal blood plasma, parenteral fluids are graded on their tonicity. Isotonic solutions have tonicity of between 280 and 300 mOsm/liter, which is within (or close to) the typical range for blood serum. The osmolality of a hypotonic solution is less than 280 μmol, whereas the salt concentration of a saturated solution is more significant than 300 mOsm/liter. This is how the three fluid categories interact with the body (Wang et al., 2014). Since the amount of solute on both surfaces of the membrane is about the same, water does not flow into or out of cells whenever an isotonic solution is instilled.

Isotonic mixtures like those with less than one percentage of sodium chloride, Ringer's lactate, Ringer's acetate, and dextrose 5 percent in water are used to enhance circulatory capacity and restore natural fluids lost. Keep a lookout for diagnoses of fluid resuscitation, particularly if the patient has a record of high blood pressure or cardiac issues because these fluids increase the intravascular section. Though D5W is isotonic in the bag, it becomes a hypotonic solution once it reaches the circulation because refined carbs like dextrose are the primary source of energy for cells.

Due to the reduced amount, the dextrose in D5W is promptly processed by the cells lining the veins and transported through the bloodstream. Use this mixture with caution in people at risk for high intraocular pressure. Lactate is transformed into bicarbonate by the liver. Therefore, don't use lactated Ringer's solution if the individual's blood pH is above 7.5 or liver difficulties; they won't soak up the lactate, increasing his metabolic acidosis.

Hypotonic (sodium chloride) solutions with 0.45 percent or 0.25 percent sodium chloride are commonly injected. Potassium chloride in low dosages can be given to restore losses from the gastrointestinal system. More water is supplied to the serum than is present within the cells when a hypotonic solution is provided. As a result, liquid enters the cells, forcing them to expand. Whereas hypotonic solutions aid in restoring the cytoplasm of the cell, the excess water at the catheter insertion site also enters the cells of the vein's tunica intima (McClelland, 2014). The cells could enlarge and break, exposing the vein's basal layer and potentially leading to phlebitis and infiltration. Infiltrate all I.V. sites for phlebitis diagnoses (erythema at the site even if there is no discomfort or swelling, perceptible venous cord, streaks development, and purulent discharge) and look for classic symptoms.

Do not use hypotonic solutions permanently since they can produce rapid fluid changes from blood arteries into cells. The nurse must avoid injecting a hypotonic solution when the patient can drink enough to fulfill their fluid demands. Failure to do so might result in a cardiovascular crash due to intravenous liquid exhaustion (Connolly, 2016). Patients treated for a stroke or brain trauma and those who have had brain surgery should avoid being given hypotonic fluids. Patients who are in a possibility for third-space fluid shifts, like those with severe burns, traumatic brain injuries, or low blood protein levels due to starvation or liver illness, should avoid hypotonic solutions as well.

Water rushes out from the cells as hypertonic solutions are administered, reducing the infuscate and causing the cells to shrink. If a patient receives a hypertonic solution, they should be constantly watched for circulation overload. Avoid hypertonic solutions if a patient has an illness that causes cellular dehydration. A person with impaired cardiac or renal function should not be given a hypertonic solution injection because his body will not handle the extra fluids.

References

Connolly, K. (2016). A Quality Improvement Initiative Aimed at Reducing Complications Related to IV Fluid Administration in the Acute Care Setting. Seton Hall University.

McClelland, M. (2014). IV therapies for patients with fluid and electrolyte imbalances. MedSurg Nursing, 23(5), S4-S4.

Wang, J., Xu, E., & Xiao, Y. (2014). Isotonic versus hypotonic maintenance IV fluids in hospitalized children: a meta-analysis. Pediatrics, 133(1), 105-113.

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